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Impact of receptor phenotype on nodal burden in patients with breast cancer who have undergone neoadjuvant chemotherapy

Hdl Handle:
http://hdl.handle.net/10147/622514
Title:
Impact of receptor phenotype on nodal burden in patients with breast cancer who have undergone neoadjuvant chemotherapy
Authors:
Boland, M. R.; McVeigh, T. P.; O'Flaherty, N.; Gullo, G.; Keane, M.; Quinn, C. M.; McDermott, E. W.; Lowery, A. J.; Kerin, M. J.; Prichard, R. S.
Citation:
Impact of receptor phenotype on nodal burden in patients with breast cancer who have undergone neoadjuvant chemotherapy 2017 BJS Open
Publisher:
BSJ Open
Journal:
BJS Open
Issue Date:
31-Jul-2017
URI:
http://hdl.handle.net/10147/622514
DOI:
10.1002/bjs5.6
Additional Links:
http://doi.wiley.com/10.1002/bjs5.6
Abstract:
Optimal evaluation and management of the axilla following neoadjuvant chemotherapy(NAC) in patients with node-positive breast cancer remains controversial. The aim of this study wasto examine the impact of receptor phenotype in patients with nodal metastases who undergo NAC to seewhether this approach can identify those who may be suitable for conservative axillary management.Methods: Between 2009 and 2014, all patients with breast cancer and biopsy-proven nodal diseasewho received NAC were identied from prospectively developed databases. Details of patients who hadaxillary lymph node dissection (ALND) following NAC were recorded and rates of pathological completeresponse (pCR) were evaluated for receptor phenotype.
Item Type:
Article
Language:
en
Keywords:
BREAST CANCER; CHEMOTHERAPY
ISSN:
24749842

Full metadata record

DC FieldValue Language
dc.contributor.authorBoland, M. R.en
dc.contributor.authorMcVeigh, T. P.en
dc.contributor.authorO'Flaherty, N.en
dc.contributor.authorGullo, G.en
dc.contributor.authorKeane, M.en
dc.contributor.authorQuinn, C. M.en
dc.contributor.authorMcDermott, E. W.en
dc.contributor.authorLowery, A. J.en
dc.contributor.authorKerin, M. J.en
dc.contributor.authorPrichard, R. S.en
dc.date.accessioned2017-08-25T11:16:25Z-
dc.date.available2017-08-25T11:16:25Z-
dc.date.issued2017-07-31-
dc.identifier.citationImpact of receptor phenotype on nodal burden in patients with breast cancer who have undergone neoadjuvant chemotherapy 2017 BJS Openen
dc.identifier.issn24749842-
dc.identifier.doi10.1002/bjs5.6-
dc.identifier.urihttp://hdl.handle.net/10147/622514-
dc.description.abstractOptimal evaluation and management of the axilla following neoadjuvant chemotherapy(NAC) in patients with node-positive breast cancer remains controversial. The aim of this study wasto examine the impact of receptor phenotype in patients with nodal metastases who undergo NAC to seewhether this approach can identify those who may be suitable for conservative axillary management.Methods: Between 2009 and 2014, all patients with breast cancer and biopsy-proven nodal diseasewho received NAC were identied from prospectively developed databases. Details of patients who hadaxillary lymph node dissection (ALND) following NAC were recorded and rates of pathological completeresponse (pCR) were evaluated for receptor phenotype.en
dc.language.isoenen
dc.publisherBSJ Openen
dc.relation.urlhttp://doi.wiley.com/10.1002/bjs5.6en
dc.rightsArchived with thanks to BJS Openen
dc.subjectBREAST CANCERen
dc.subjectCHEMOTHERAPYen
dc.titleImpact of receptor phenotype on nodal burden in patients with breast cancer who have undergone neoadjuvant chemotherapyen
dc.typeArticleen
dc.identifier.journalBJS Openen
dc.description.fundingNo fundingen
dc.description.provinceLeinsteren
dc.description.peer-reviewpeer-reviewen
dc.contributor.institutionDepartment of Breast Surgery; St Vincent's University Hospital; Dublin Ireland-
dc.contributor.institutionDepartment of Breast Surgery; University College Hospital Galway; Galway Ireland-
dc.contributor.institutionDepartment of Breast Surgery; University College Hospital Galway; Galway Ireland-
dc.contributor.institutionDepartment of Oncology; St Vincent's University Hospital; Dublin Ireland-
dc.contributor.institutionDepartment of Oncology; University College Hospital Galway; Galway Ireland-
dc.contributor.institutionDepartment of Pathology; St Vincent's University Hospital; Dublin Ireland-
dc.contributor.institutionDepartment of Breast Surgery; St Vincent's University Hospital; Dublin Ireland-
dc.contributor.institutionDepartment of Breast Surgery; University College Hospital Galway; Galway Ireland-
dc.contributor.institutionDepartment of Breast Surgery; University College Hospital Galway; Galway Ireland-
dc.contributor.institutionDepartment of Breast Surgery; St Vincent's University Hospital; Dublin Ireland-
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