Urinary Phthalate Concentrations in Mothers and Their Children in Ireland: Results of the DEMOCOPHES Human Biomonitoring Study.

Hdl Handle:
http://hdl.handle.net/10147/622685
Title:
Urinary Phthalate Concentrations in Mothers and Their Children in Ireland: Results of the DEMOCOPHES Human Biomonitoring Study.
Authors:
Health Service Executive (HSE); Cullen, Elizabeth; Evans, David; Griffin, Chris; Burke, Padraig; Mannion, Rory; Burns, Damien; Flanagan, Andrew; Kellegher, Ann; Schoeters, Greet; Govarts, Eva; Biot, Pierre; Casteleyn, Ludwine; Castaño, Argelia; Kolossa-Gehring, Marike; Esteban, Marta; Schwedler, Gerda; Koch, Holger M; Angerer, Jürgen; Knudsen, Lisbeth E; Joas, Reinhard; Joas, Anke; Dumez, Birgit; Sepai, Ovnair; Exley, Karen; Aerts, Dominique
Citation:
Urinary Phthalate Concentrations in Mothers and Their Children in Ireland: Results of the DEMOCOPHES Human Biomonitoring Study. 2017, 14 (12) Int J Environ Res Public Health
Publisher:
Health Service Executive (HSE)
Journal:
International journal of environmental research and public health
Issue Date:
25-Nov-2017
URI:
http://hdl.handle.net/10147/622685
DOI:
10.3390/ijerph14121456
PubMed ID:
29186834
Additional Links:
http://www.mdpi.com/1660-4601/14/12/1456/htm
Abstract:
Background: Phthalates are chemicals which are widespread in the environment. Although the impacts on health of such exposure are unclear, there is evidence of a possible impact on the incidence of a diverse range of diseases. Monitoring of human exposure to phthalates is therefore important. This study aimed to determine the extent of phthalate exposure among mothers and their children in both rural and urban areas in Ireland, and to identify factors associated with elevated concentrations. It formed part of the 'Demonstration of a study to Co-ordinate and Perform Human Biomonitoring on a European Scale' (DEMOCOPHES) pilot biomonitoring study. Methods: the concentration of phthalate metabolites were determined from a convenience sample of 120 mother/child pairs. The median age of the children was 8 years. A questionnaire was used to collect information regarding lifestyle and environmental conditions of the children and mothers. Rigorous quality assurance within DEMOCOPHES guaranteed the accuracy and international comparability of results. Results: Phthalate metabolites were detected in all of the samples from both children and mothers. Concentrations were significantly higher in respondents from families with lower educational attainment and in those exposed to such items as polyvinyl chloride (PVC), fast food and personal care products (PCP). Conclusions: The study demonstrates that human biomonitoring for assessing exposure to phthalates can be undertaken in Ireland and that the exposure of the population is widespread. Further work will be necessary before the consequences of this exposure are understood.
Item Type:
Article
Language:
en
Description:
Phthalates are chemicals which are widespread in the environment. Although the impacts on health of such exposure are unclear, there is evidence of a possible impact on the incidence of a diverse range of diseases. Monitoring of human exposure to phthalates is therefore important. This study aimed to determine the extent of phthalate exposure among mothers and their children in both rural and urban areas in Ireland, and to identify factors associated with elevated concentrations. It formed part of the 'Demonstration of a study to Co-ordinate and Perform Human Biomonitoring on a European Scale' (DEMOCOPHES) pilot biomonitoring study. Methods: the concentration of phthalate metabolites were determined from a convenience sample of 120 mother/child pairs. The median age of the children was 8 years. A questionnaire was used to collect information regarding lifestyle and environmental conditions of the children and mothers. Rigorous quality assurance within DEMOCOPHES guaranteed the accuracy and international comparability of results. Results: Phthalate metabolites were detected in all of the samples from both children and mothers. Concentrations were significantly higher in respondents from families with lower educational attainment and in those exposed to such items as polyvinyl chloride (PVC), fast food and personal care products (PCP).
Local subject classification:
PUBLIC HEALTH DEPARTMENT; ENVIRONMENT AND HEALTH; HEALTH PROTECTION
ISSN:
1660-4601

Full metadata record

DC FieldValue Language
dc.contributor.authorHealth Service Executive (HSE)en
dc.contributor.authorCullen, Elizabethen
dc.contributor.authorEvans, Daviden
dc.contributor.authorGriffin, Chrisen
dc.contributor.authorBurke, Padraigen
dc.contributor.authorMannion, Roryen
dc.contributor.authorBurns, Damienen
dc.contributor.authorFlanagan, Andrewen
dc.contributor.authorKellegher, Annen
dc.contributor.authorSchoeters, Greeten
dc.contributor.authorGovarts, Evaen
dc.contributor.authorBiot, Pierreen
dc.contributor.authorCasteleyn, Ludwineen
dc.contributor.authorCastaño, Argeliaen
dc.contributor.authorKolossa-Gehring, Marikeen
dc.contributor.authorEsteban, Martaen
dc.contributor.authorSchwedler, Gerdaen
dc.contributor.authorKoch, Holger Men
dc.contributor.authorAngerer, Jürgenen
dc.contributor.authorKnudsen, Lisbeth Een
dc.contributor.authorJoas, Reinharden
dc.contributor.authorJoas, Ankeen
dc.contributor.authorDumez, Birgiten
dc.contributor.authorSepai, Ovnairen
dc.contributor.authorExley, Karenen
dc.contributor.authorAerts, Dominiqueen
dc.date.accessioned2017-12-05T10:42:27Z-
dc.date.available2017-12-05T10:42:27Z-
dc.date.issued2017-11-25-
dc.identifier.citationUrinary Phthalate Concentrations in Mothers and Their Children in Ireland: Results of the DEMOCOPHES Human Biomonitoring Study. 2017, 14 (12) Int J Environ Res Public Healthen
dc.identifier.issn1660-4601-
dc.identifier.pmid29186834-
dc.identifier.doi10.3390/ijerph14121456-
dc.identifier.urihttp://hdl.handle.net/10147/622685-
dc.descriptionPhthalates are chemicals which are widespread in the environment. Although the impacts on health of such exposure are unclear, there is evidence of a possible impact on the incidence of a diverse range of diseases. Monitoring of human exposure to phthalates is therefore important. This study aimed to determine the extent of phthalate exposure among mothers and their children in both rural and urban areas in Ireland, and to identify factors associated with elevated concentrations. It formed part of the 'Demonstration of a study to Co-ordinate and Perform Human Biomonitoring on a European Scale' (DEMOCOPHES) pilot biomonitoring study. Methods: the concentration of phthalate metabolites were determined from a convenience sample of 120 mother/child pairs. The median age of the children was 8 years. A questionnaire was used to collect information regarding lifestyle and environmental conditions of the children and mothers. Rigorous quality assurance within DEMOCOPHES guaranteed the accuracy and international comparability of results. Results: Phthalate metabolites were detected in all of the samples from both children and mothers. Concentrations were significantly higher in respondents from families with lower educational attainment and in those exposed to such items as polyvinyl chloride (PVC), fast food and personal care products (PCP).en
dc.description.abstractBackground: Phthalates are chemicals which are widespread in the environment. Although the impacts on health of such exposure are unclear, there is evidence of a possible impact on the incidence of a diverse range of diseases. Monitoring of human exposure to phthalates is therefore important. This study aimed to determine the extent of phthalate exposure among mothers and their children in both rural and urban areas in Ireland, and to identify factors associated with elevated concentrations. It formed part of the 'Demonstration of a study to Co-ordinate and Perform Human Biomonitoring on a European Scale' (DEMOCOPHES) pilot biomonitoring study. Methods: the concentration of phthalate metabolites were determined from a convenience sample of 120 mother/child pairs. The median age of the children was 8 years. A questionnaire was used to collect information regarding lifestyle and environmental conditions of the children and mothers. Rigorous quality assurance within DEMOCOPHES guaranteed the accuracy and international comparability of results. Results: Phthalate metabolites were detected in all of the samples from both children and mothers. Concentrations were significantly higher in respondents from families with lower educational attainment and in those exposed to such items as polyvinyl chloride (PVC), fast food and personal care products (PCP). Conclusions: The study demonstrates that human biomonitoring for assessing exposure to phthalates can be undertaken in Ireland and that the exposure of the population is widespread. Further work will be necessary before the consequences of this exposure are understood.-
dc.language.isoenen
dc.publisherHealth Service Executive (HSE)en
dc.relation.urlhttp://www.mdpi.com/1660-4601/14/12/1456/htmen
dc.rightsArchived with thanks to International journal of environmental research and public healthen
dc.subject.otherPUBLIC HEALTH DEPARTMENTen
dc.subject.otherENVIRONMENT AND HEALTHen
dc.subject.otherHEALTH PROTECTIONen
dc.titleUrinary Phthalate Concentrations in Mothers and Their Children in Ireland: Results of the DEMOCOPHES Human Biomonitoring Study.en
dc.typeArticleen
dc.identifier.journalInternational journal of environmental research and public healthen

Related articles on PubMed

All Items in Lenus, The Irish Health Repository are protected by copyright, with all rights reserved, unless otherwise indicated.