• Cardiovascular risk age: concepts and practicalities.

      Cooney, Marie Therese; Vartiainen, Erkki; Laatikainen, Tiina; De Bacquer, Dirk; McGorrian, Catherine; Dudina, Alexandra; Graham, Ian; Department of Cardiology, Adelaide Meath Hospital, Dublin, Ireland. (2012-06)
      A young person with many risk factors may have the same level of risk as an older person with no risk factors. Thus a high-risk 40-year-old may have a risk age of 60 years or more. The aim of the study was to derive a generic equation for risk age, construct risk age charts, and explore the hypothesis that risk age is similar regardless of the cardiovascular disease (CVD) end point used.
    • Elevated resting heart rate is an independent risk factor for cardiovascular disease in healthy men and women.

      Cooney, Marie Therese; Vartiainen, Erkki; Laatikainen, Tiina; Juolevi, Anne; Dudina, Alexandra; Graham, Ian M; Department of Cardiology, Adelaide Meath Hospital, Tallaght, Dublin 24, Ireland. (American heart journal, 2010-04)
      Elevated resting heart rate (RHR) is known to be associated with reduced survival but inconsistencies remain, including lack of significance in most studies of healthy women, lack of independence from systolic blood pressure (SBP) in some, and the suggestion that RHR is merely functioning as a marker of physical inactivity or other comorbidities. We aimed to clarify these inconsistencies.
    • Simplifying cardiovascular risk estimation using resting heart rate.

      Cooney, Marie Therese; Vartiainen, Erkki; Laatikainen, Tiina; Joulevi, Anne; Dudina, Alexandra; Graham, Ian; Department of Cardiology, Adelaide Meath Hospital, Tallaght, Dublin 24, Ireland. (European heart journal, 2010-09)
      Elevated resting heart rate (RHR) is a known, independent cardiovascular (CV) risk factor, but is not included in risk estimation systems, including Systematic COronary Risk Evaluation (SCORE). We aimed to derive risk estimation systems including RHR as an extra variable and assess the value of this addition.