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dc.contributor.authorRowland, Marion
dc.contributor.authorFleming, Paddy
dc.contributor.authorBourke, Billy
dc.date.accessioned2011-03-14T15:34:49Z
dc.date.available2011-03-14T15:34:49Z
dc.date.issued2010-02
dc.identifier.citationLooking in the mouth for Crohn's disease. 2010, 16 (2):332-7 Inflamm. Bowel Dis.en
dc.identifier.issn1536-4844
dc.identifier.pmid19705418
dc.identifier.doi10.1002/ibd.20983
dc.identifier.urihttp://hdl.handle.net/10147/124496
dc.description.abstractIt is widely acknowledged among gastroenterologists that the oral cavity may be involved in Crohn's disease (CD). However, the specific manifestations are poorly appreciated. Although oral aphthous ulceration is probably not diagnostically useful in patients with suspected CD, disease-specific manifestations do occur and are particularly common in children presenting with CD. These manifestations can be subtle, often are subclinical, yet commonly harbor diagnostically useful material (granulomas). Orofacial granulomatosis (OFG) is conventionally used to describe patients with overt oral disease without obvious involvement of the gastrointestinal tract. However, many patients with OFG have subclinical intestinal CD or will progress to develop overt intestinal CD with time. The management of severe oral disease is challenging and lacks a clear evidence base.
dc.language.isoenen
dc.subject.meshAdult
dc.subject.meshChild
dc.subject.meshCrohn Disease
dc.subject.meshDisease Progression
dc.subject.meshHumans
dc.subject.meshMouth Diseases
dc.subject.meshOral Ulcer
dc.subject.meshRemission, Spontaneous
dc.titleLooking in the mouth for Crohn's disease.en
dc.typeArticleen
dc.contributor.departmentUCD School of Medicine & Medical Science, Crumlin, Dublin, Ireland.en
dc.identifier.journalInflammatory bowel diseasesen
dc.description.provinceLeinster
html.description.abstractIt is widely acknowledged among gastroenterologists that the oral cavity may be involved in Crohn's disease (CD). However, the specific manifestations are poorly appreciated. Although oral aphthous ulceration is probably not diagnostically useful in patients with suspected CD, disease-specific manifestations do occur and are particularly common in children presenting with CD. These manifestations can be subtle, often are subclinical, yet commonly harbor diagnostically useful material (granulomas). Orofacial granulomatosis (OFG) is conventionally used to describe patients with overt oral disease without obvious involvement of the gastrointestinal tract. However, many patients with OFG have subclinical intestinal CD or will progress to develop overt intestinal CD with time. The management of severe oral disease is challenging and lacks a clear evidence base.


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