• Transitioning high sensitivity cardiac troponin I (hs-cTnI) into routine diagnostic use: More than just a sensitivity issue

      Lee, Graham R; Browne, Tara CA; Guest, Berna; Khan, Imran; Murphy, Eamon; McGorrian, Catherine; Mahon, Niall G; Fitzgibbon, Maria C (Practical Laboratory Medicine, 2016-04)
      High sensitivity cardiac troponin T and I (hs-cTnT and hs-cTnI) assays show analytical, diagnostic and prognostic improvement over contemporary sensitive cTn assays. However, given the importance of troponin in the diagnosis of myocardial infarction, implementing this test requires rigorous analytical and clinical verification across the total testing pathway. This was the aim of this study.