Browsing National Maternity Hospital Holles St. by Subjects
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Effect of injury on S1 dorsal root ganglia in an experimental model of neuropathic faecal incontinence.An experimental model of neuropathic faecal incontinence has recently been established. This study aimed to quantify and compare the effect of crush and compression injury on first-order sensory neurones of the inferior rectal nerve (IRN) using a nuclear marker of axonal injury, activating transcription factor (ATF) 3.
Sacral nerve stimulation increases activation of the primary somatosensory cortex by anal canal stimulation in an experimental model.Sacral and posterior tibial nerve stimulation may be used to treat faecal incontinence; however, the mechanism of action is unknown. The aim of this study was to establish whether sensory activation of the cerebral cortex by anal canal stimulation was increased by peripheral neuromodulation.