• Soluble triggering receptor expressed on myeloid cells-1 (strem-1) in neonatal sepsis

      O'Currain, E; Doughty, C; Smith, S; Grant, T; O'Hare, F; Culliton, M; Watson, R; O'Neill, A; Molloy, EJ (Pediatric Research, 2011-11)
    • Toll-like receptors in neonatal sepsis.

      O'Hare, Fiona M; William Watson, R; Molloy, Eleanor J (2013-06)
      Toll-like receptors are vital transmembrane receptors that initiate the innate immune response to many micro-organisms. The discovery of these receptors has improved our understanding of host-pathogen interactions, and these receptors play an important role in the pathogenesis of multiple neonatal conditions such as sepsis and brain injury. Toll-like receptors, especially TLRs 2 and 4, are associated with necrotizing enterocolitis, periventricular leukomalacia and sepsis.