• Cardiac biomarkers in neonatal hypoxic ischaemia.

      Sweetman, D; Armstrong, K; Murphy, J F A; Molloy, E J; Neonatology, National Maternity Hospital, Dublin, Ireland. dsweetman@nmh.ie (2012-04)
      Following a perinatal hypoxic-ischaemic insult, term infants commonly develop cardiovascular dysfunction. Troponin-T, troponin-I and brain natriuretic peptide are sensitive indicators of myocardial compromise. The long-term effects of cardiovascular dysfunction on neurodevelopmental outcome following perinatal hypoxic ischaemia remain controversial. Follow-up studies are warranted to ensure optimal cardiac function in adulthood. CONCLUSION: Cardiac biomarkers may improve the diagnosis of myocardial injury, help guide management, estimate mortality risk and may also aid in longterm neurodevelopmental outcome prediction following neonatal hypoxic-ischaemia.