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dc.contributor.authorSavoye, Mary
dc.contributor.authorNowicka, Paulina
dc.contributor.authorShaw, Melissa
dc.contributor.authorYu, Sunkyung
dc.contributor.authorDziura, James
dc.contributor.authorChavent, Georgia
dc.contributor.authorO'Malley, Grace
dc.contributor.authorSerrecchia, John B
dc.contributor.authorTamborlane, William V
dc.contributor.authorCaprio, Sonia
dc.date.accessioned2011-11-01T11:53:47Z
dc.date.available2011-11-01T11:53:47Z
dc.date.issued2011-03
dc.identifier.citationLong-term results of an obesity program in an ethnically diverse pediatric population. 2011, 127 (3):402-10 Pediatricsen
dc.identifier.issn1098-4275
dc.identifier.pmid21300674
dc.identifier.doi10.1542/peds.2010-0697
dc.identifier.urihttp://hdl.handle.net/10147/188294
dc.description.abstractTo determine if beneficial effects of a weight-management program could be sustained for up to 24 months in a randomized trial in an ethnically diverse obese population.
dc.description.abstractThere were 209 obese children (BMI > 95th percentile), ages 8 to 16 of mixed ethnic backgrounds randomly assigned to the intensive lifestyle intervention or clinic control group. The control group received counseling every 6 months, and the intervention group received a family-based program, which included exercise, nutrition, and behavior modification. Lifestyle intervention sessions occurred twice weekly for the first 6 months, then twice monthly for the second 6 months; for the last 12 months there was no active intervention. There were 174 children who completed the 12 months of the randomized trial. Follow-up data were available for 76 of these children at 24 months. There were no statistical differences in dropout rates among ethnic groups or in any other aspects.
dc.description.abstractTreatment effect was sustained at 24 months in the intervention versus control group for BMI z score (-0.16 [95% confidence interval: -0.23 to -0.09]), BMI (-2.8 kg/m(2) [95% confidence interval: -4.0-1.6 kg/m(2)]), percent body fat (-4.2% [95% confidence interval: -6.4% to -2.0%]), total body fat mass (-5.8 kg [95% confidence interval: -9.1 kg to -2.6 kg]), total cholesterol (-13.0 mg/dL [95% confidence interval: -21.7 mg/dL to -4.2 mg/dL]), low-density lipoprotein cholesterol (-10.4 mg/dL [95% confidence interval: -18.3 mg/dL to -2.4 mg/dL]), and homeostasis model assessment of insulin resistance (-2.05 [95% confidence interval: -2.48 to -1.75]).
dc.description.abstractThis study, unprecedented because of the high degree of obesity and ethnically diverse backgrounds of children, reveals that benefits of an intensive lifestyle program can be sustained 12 months after completing the active intervention phase.
dc.description.sponsorshipIrish Fulbright Commissionen
dc.language.isoenen
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pubmed/21300674en
dc.subject.meshAdolescent
dc.subject.meshBehavior Therapy
dc.subject.meshBody Mass Index
dc.subject.meshChild
dc.subject.meshCounseling
dc.subject.meshDiet, Reducing
dc.subject.meshEthnic Groups
dc.subject.meshExercise Therapy
dc.subject.meshFollow-Up Studies
dc.subject.meshHumans
dc.subject.meshObesity
dc.subject.meshRetrospective Studies
dc.subject.meshTime Factors
dc.subject.meshTreatment Outcome
dc.subject.meshWeight Loss
dc.titleLong-term results of an obesity program in an ethnically diverse pediatric population.en
dc.typeArticle In Pressen
dc.contributor.departmentYale University School of Medicine, Pediatric Endocrinology, PO Box 208064, New Haven, CT 06520-8064, USA. mary.savoye@yale.eduen
dc.identifier.journalPediatricsen
dc.description.provinceLeinster
html.description.abstractTo determine if beneficial effects of a weight-management program could be sustained for up to 24 months in a randomized trial in an ethnically diverse obese population.
html.description.abstractThere were 209 obese children (BMI > 95th percentile), ages 8 to 16 of mixed ethnic backgrounds randomly assigned to the intensive lifestyle intervention or clinic control group. The control group received counseling every 6 months, and the intervention group received a family-based program, which included exercise, nutrition, and behavior modification. Lifestyle intervention sessions occurred twice weekly for the first 6 months, then twice monthly for the second 6 months; for the last 12 months there was no active intervention. There were 174 children who completed the 12 months of the randomized trial. Follow-up data were available for 76 of these children at 24 months. There were no statistical differences in dropout rates among ethnic groups or in any other aspects.
html.description.abstractTreatment effect was sustained at 24 months in the intervention versus control group for BMI z score (-0.16 [95% confidence interval: -0.23 to -0.09]), BMI (-2.8 kg/m(2) [95% confidence interval: -4.0-1.6 kg/m(2)]), percent body fat (-4.2% [95% confidence interval: -6.4% to -2.0%]), total body fat mass (-5.8 kg [95% confidence interval: -9.1 kg to -2.6 kg]), total cholesterol (-13.0 mg/dL [95% confidence interval: -21.7 mg/dL to -4.2 mg/dL]), low-density lipoprotein cholesterol (-10.4 mg/dL [95% confidence interval: -18.3 mg/dL to -2.4 mg/dL]), and homeostasis model assessment of insulin resistance (-2.05 [95% confidence interval: -2.48 to -1.75]).
html.description.abstractThis study, unprecedented because of the high degree of obesity and ethnically diverse backgrounds of children, reveals that benefits of an intensive lifestyle program can be sustained 12 months after completing the active intervention phase.


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