The effectiveness of methicillin-resistant Staphylococcus aureus colonisation screening in asymptomatic healthcare workers in an Irish orthopaedic unit.
AffiliationDepartment of Trauma and Orthopaedics, Mayo General Hospital, Castlebar, County, Mayo, Ireland. email@example.com
Anti-Infective Agents, Local/administration & dosage
Carrier State/diagnosis/drug therapy/*epidemiology/microbiology
Methicillin-Resistant Staphylococcus aureus/*isolation & purification
Mupirocin/administration & dosage
Staphylococcal Infections/diagnosis/drug therapy/*epidemiology/microbiology
MetadataShow full item record
CitationEur J Clin Microbiol Infect Dis. 2011 Sep;30(9):1063-6. Epub 2011 Feb 12.
JournalEuropean journal of clinical microbiology & infectious diseases : official, publication of the European Society of Clinical Microbiology
AbstractMethicillin-resistant Staphylococcus aureus (MRSA) infections are associated with increased mortality, costs and length of stay compared to non-MRSA infections. This observational 4-year study analyses the impact of screening and treating orthopaedic healthcare workers for MRSA colonisation. A total of 1,011 swabs were taken from 566 healthcare workers. Positive healthcare workers were treated with topical mupirocin to both anterior nares. The prevalence of MRSA colonisation on initial testing was 4.77%. The rate of positive MRSA colonisation of those tested on more than one occasion fell from 5.88% to 2.71% (p = 0.055) on subsequent screening. All healthcare workers receiving treatment were successfully cleared of colonisation; however, some required more than one course of treatment. These results show that there could be a role for screening and treating orthopaedic staff for MRSA colonisation as part of a strategy to reduce the prevalence of MRSA infections in orthopaedic units.