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dc.contributor.authorWalsh, Brian H
dc.contributor.authorLow, Evonne
dc.contributor.authorBogue, Conor O
dc.contributor.authorMurray, Deirdre M
dc.contributor.authorBoylan, Geraldine B
dc.date.accessioned2012-01-31T16:43:31Z
dc.date.available2012-01-31T16:43:31Z
dc.date.issued2012-01-31T16:43:31Z
dc.identifier.citationDev Med Child Neurol. 2011 Jan;53(1):89-92. doi:, 10.1111/j.1469-8749.2010.03837.x. Epub 2010 Nov 18.en_GB
dc.identifier.issn1469-8749 (Electronic)en_GB
dc.identifier.issn0012-1622 (Linking)en_GB
dc.identifier.pmid21087242en_GB
dc.identifier.doi10.1111/j.1469-8749.2010.03837.xen_GB
dc.identifier.urihttp://hdl.handle.net/10147/205804
dc.description.abstractPerinatal stroke is the second most common cause of neonatal seizures, and can result in long-term neurological impairment. Diagnosis is often delayed until after seizure onset, owing to the subtle nature of associated signs. We report the early electroencephalographic (EEG) findings in a female infant with a perinatal infarction, born at 41 weeks 2 days and weighing 3.42 kg. Before the onset of seizures, the EEG from 3 hours after delivery demonstrated occasional focal sharp waves over the affected region. After electroclinical seizures, focal sharp waves became more frequent, complex, and of higher amplitude, particularly in 'quiet sleep'. In 'active sleep', sharp waves often disappeared. Diffusion-weighted imaging confirmed the infarct, demonstrating left frontal and parietal diffusion restriction. At 9 months, the infant has had no further seizures, and neurological examination is normal. To our knowledge, this report is the first to describe the EEG findings in perinatal stroke before seizures, and highlights the evolution of characteristic background EEG features.
dc.language.isoengen_GB
dc.subject.mesh*Electroencephalographyen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshHumansen_GB
dc.subject.meshInfant, Newbornen_GB
dc.subject.meshIntensive Care Unitsen_GB
dc.subject.meshSeizures/etiologyen_GB
dc.subject.meshSleep/physiologyen_GB
dc.subject.meshStroke/*physiopathologyen_GB
dc.subject.mesh*Videotape Recordingen_GB
dc.titleEarly continuous video electroencephalography in neonatal stroke.en_GB
dc.contributor.departmentNeonatal Brain Research Group, Cork University Maternity Hospital, Wilton, Cork, , Ireland. Bh.walsh@ucc.ieen_GB
dc.identifier.journalDevelopmental medicine and child neurologyen_GB
dc.description.provinceMunster
html.description.abstractPerinatal stroke is the second most common cause of neonatal seizures, and can result in long-term neurological impairment. Diagnosis is often delayed until after seizure onset, owing to the subtle nature of associated signs. We report the early electroencephalographic (EEG) findings in a female infant with a perinatal infarction, born at 41 weeks 2 days and weighing 3.42 kg. Before the onset of seizures, the EEG from 3 hours after delivery demonstrated occasional focal sharp waves over the affected region. After electroclinical seizures, focal sharp waves became more frequent, complex, and of higher amplitude, particularly in 'quiet sleep'. In 'active sleep', sharp waves often disappeared. Diffusion-weighted imaging confirmed the infarct, demonstrating left frontal and parietal diffusion restriction. At 9 months, the infant has had no further seizures, and neurological examination is normal. To our knowledge, this report is the first to describe the EEG findings in perinatal stroke before seizures, and highlights the evolution of characteristic background EEG features.


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