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    Palivizumab use in preterm neonates.

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    Authors
    Kingston, S
    Murphy, B P
    Affiliation
    Department of Neonatology, Cork University Maternity Hospital, Wilton, Cork.
    Issue Date
    2012-01-31T16:43:43Z
    MeSH
    Antibodies, Monoclonal/*therapeutic use
    Antibodies, Monoclonal, Humanized
    Antiviral Agents/*therapeutic use
    Bronchiolitis/*prevention & control/virology
    Clinical Protocols
    Female
    Guideline Adherence
    Humans
    Infant, Newborn
    *Infant, Premature
    Ireland
    Male
    Physician's Practice Patterns/*statistics & numerical data
    Questionnaires
    Respiratory Syncytial Virus Infections/*prevention & control
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    Citation
    Ir Med J. 2010 May;103(5):141-4.
    Journal
    Irish medical journal
    URI
    http://hdl.handle.net/10147/206211
    PubMed ID
    20666085
    Abstract
    Respiratory syncytial virus (RSV) is the leading cause of bronchiolitis in infants. Palivizumab is an immunoprophylactic agent for RSV prevention in preterm infants and those with neonatal chronic lung disease. This study examines its use across neonatal units in Ireland. A questionnaire was administered to one Consultant Neonatologist or Paediatrician in each of the 20 maternity centres in Ireland about their guidelines for Palivizumab administration. There is variation in administration of Palivizumab with little consistency found between protocols reported in terms of age and presence of chronic lung disease. Ten centres have in house protocols, 3 centres use the American Academy of Paediatrics (AAP) guidelines, 2 centres prefer the UK Joint Committee on Vaccination and Immunisation (JCVI) guidelines and 3 centres do not have a set protocol. Four participants felt its use has impacted on hospital admissions and 61% believe its use is cost effective. The budgetary implication for immunoprophylaxis with Palivizumab in Ireland is estimated at 1.5 to 2 million euros annually. Given current pharmacoeconomic constraints there is a need to implement a national protocol on RSV immunoprophylaxis.
    Language
    eng
    ISSN
    0332-3102 (Print)
    0332-3102 (Linking)
    Collections
    Cork University Maternity Hospital

    entitlement

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