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dc.contributor.authorRowland, Marion
dc.contributor.authorFleming, Paddy
dc.contributor.authorBourke, Billy
dc.date.accessioned2012-02-01T10:25:01Z
dc.date.available2012-02-01T10:25:01Z
dc.date.issued2012-02-01T10:25:01Z
dc.identifier.citationInflamm Bowel Dis. 2010 Feb;16(2):332-7.en_GB
dc.identifier.issn1536-4844 (Electronic)en_GB
dc.identifier.issn1078-0998 (Linking)en_GB
dc.identifier.pmid19705418en_GB
dc.identifier.doi10.1002/ibd.20983en_GB
dc.identifier.urihttp://hdl.handle.net/10147/207438
dc.description.abstractIt is widely acknowledged among gastroenterologists that the oral cavity may be involved in Crohn's disease (CD). However, the specific manifestations are poorly appreciated. Although oral aphthous ulceration is probably not diagnostically useful in patients with suspected CD, disease-specific manifestations do occur and are particularly common in children presenting with CD. These manifestations can be subtle, often are subclinical, yet commonly harbor diagnostically useful material (granulomas). Orofacial granulomatosis (OFG) is conventionally used to describe patients with overt oral disease without obvious involvement of the gastrointestinal tract. However, many patients with OFG have subclinical intestinal CD or will progress to develop overt intestinal CD with time. The management of severe oral disease is challenging and lacks a clear evidence base.
dc.language.isoengen_GB
dc.subject.meshAdulten_GB
dc.subject.meshChilden_GB
dc.subject.meshCrohn Disease/complications/*diagnosis/pathologyen_GB
dc.subject.meshDisease Progressionen_GB
dc.subject.meshHumansen_GB
dc.subject.meshMouth Diseases/diagnosis/*etiology/pathology/therapyen_GB
dc.subject.meshOral Ulcer/diagnosis/etiology/pathology/therapyen_GB
dc.subject.meshRemission, Spontaneousen_GB
dc.titleLooking in the mouth for Crohn's disease.en_GB
dc.contributor.departmentUCD School of Medicine & Medical Science, Crumlin, Dublin, Ireland.en_GB
dc.identifier.journalInflammatory bowel diseasesen_GB
dc.description.provinceLeinster
html.description.abstractIt is widely acknowledged among gastroenterologists that the oral cavity may be involved in Crohn's disease (CD). However, the specific manifestations are poorly appreciated. Although oral aphthous ulceration is probably not diagnostically useful in patients with suspected CD, disease-specific manifestations do occur and are particularly common in children presenting with CD. These manifestations can be subtle, often are subclinical, yet commonly harbor diagnostically useful material (granulomas). Orofacial granulomatosis (OFG) is conventionally used to describe patients with overt oral disease without obvious involvement of the gastrointestinal tract. However, many patients with OFG have subclinical intestinal CD or will progress to develop overt intestinal CD with time. The management of severe oral disease is challenging and lacks a clear evidence base.


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