First Irish birth following IVF therapy using antagonist protocol.
AffiliationHARI Unit, Rotunda Hospital, Dublin 1, Ireland. email@example.com
Fertilization in Vitro/*methods
Follicle Stimulating Hormone, Human/administration & dosage
Gonadotropin-Releasing Hormone/administration & dosage/*analogs &
derivatives/*antagonists & inhibitors
Zygote Intrafallopian Transfer
MetadataShow full item record
CitationIr J Med Sci. 2010 Sep;179(3):455-7. Epub 2009 Apr 4.
JournalIrish journal of medical science
AbstractBACKGROUND: During in vitro fertilization (IVF), the prevention of a premature LH surge was traditionally achieved using a gonadotrophin releasing hormone agonist (GnRH-a), and more recently, a GnRH antagonist. AIMS: We report a case of a 37 year old treated using the GnRH antagonist in a second completed cycle of IVF. METHODS: IVF was performed for primary infertility of 5-year duration due to frozen pelvis secondary to endometriosis. RESULTS: Following controlled ovarian hyperstimulation, oocyte recovery and fertilization, cleavage and transfer of two zygotes, a pregnancy established. A twin gestation was diagnosed at 7-weeks scan and pregnancy ended with the delivery of twin girls by emergency caesarean section. CONCLUSION: This is a first report of a delivery following IVF using the antagonist protocol in Ireland. Such therapy is patient friendly and its use should be introduced on a larger scale in clinical practice.
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