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dc.contributor.authorO'Sullivan, A
dc.contributor.authorO'Connor, M
dc.contributor.authorBrosnahan, D
dc.contributor.authorMcCreery, K
dc.contributor.authorDempsey, E M
dc.date.accessioned2012-02-01T10:56:57Z
dc.date.available2012-02-01T10:56:57Z
dc.date.issued2012-02-01T10:56:57Z
dc.identifier.citationArch Dis Child Fetal Neonatal Ed. 2010 Nov;95(6):F419-22. Epub 2010 Sep 28.en_GB
dc.identifier.issn1468-2052 (Electronic)en_GB
dc.identifier.issn1359-2998 (Linking)en_GB
dc.identifier.pmid20876596en_GB
dc.identifier.doi10.1136/adc.2009.180943en_GB
dc.identifier.urihttp://hdl.handle.net/10147/207990
dc.description.abstractOBJECTIVE: To assess the efficacy of oral sucrose combined with swaddling and non-nutritive suck (NNS) as a method for reducing pain associated with retinopathy of prematurity (ROP) screening. DESIGN: Randomised placebo controlled study. SETTING: Tertiary level neonatal intensive care unit. SAMPLE: 40 infants undergoing primary eye examination for ROP screening. INTERVENTION: The control group were swaddled, and received 0.2 ml of sterile water given by mouth using a syringe and a soother. The intervention group were swaddled, and received 0.2 ml of sucrose 24% given by mouth using a syringe and a soother. RESULTS: 40 infants were included in the study. There was no difference in mean gestational age at birth, mean birth weight or corrected gestational age at first examination between both groups. The sucrose group had a significantly lower median Neonatal Pain, Agitation and Sedation Scale (N-PASS) score during ROP screening, initially following insertion of the speculum (6.5 vs 5, p=0.02) and subsequently during scleral indentation (9.5 vs 7.5, p=0.03). Fewer infants experienced episodes of desaturations or bradycardia in the intervention group (1 vs 4, p=0.18). CONCLUSION: ROP screening is a necessary but recognised painful procedure. Sucrose combined with NNS and swaddling reduced the behavioural and physiological pain responses. However, pain scores remained consistently high and appropriate pain relief for ROP screening remains a challenge.
dc.language.isoengen_GB
dc.subject.meshAdministration, Oralen_GB
dc.subject.meshAnalgesia/*methodsen_GB
dc.subject.meshAnalgesics/administration & dosageen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshHumansen_GB
dc.subject.meshInfant Care/methodsen_GB
dc.subject.meshInfant, Newbornen_GB
dc.subject.meshInfant, Prematureen_GB
dc.subject.meshIntensive Care, Neonatal/methodsen_GB
dc.subject.meshMaleen_GB
dc.subject.meshNeonatal Screening/*adverse effects/methodsen_GB
dc.subject.mesh*Pacifiersen_GB
dc.subject.meshPain/etiology/*prevention & controlen_GB
dc.subject.meshPain Measurement/methodsen_GB
dc.subject.meshPhysical Examination/adverse effects/methodsen_GB
dc.subject.meshProspective Studiesen_GB
dc.subject.meshRetinopathy of Prematurity/*diagnosisen_GB
dc.subject.meshSucrose/administration & dosageen_GB
dc.titleSweeten, soother and swaddle for retinopathy of prematurity screening: a randomised placebo controlled trial.en_GB
dc.contributor.departmentDepartment of Paediatrics and Newborn Medicine, Coombe Women and Infants, University Hospital, Dublin, Ireland.en_GB
dc.identifier.journalArchives of disease in childhood. Fetal and neonatal editionen_GB
dc.description.provinceLeinster
html.description.abstractOBJECTIVE: To assess the efficacy of oral sucrose combined with swaddling and non-nutritive suck (NNS) as a method for reducing pain associated with retinopathy of prematurity (ROP) screening. DESIGN: Randomised placebo controlled study. SETTING: Tertiary level neonatal intensive care unit. SAMPLE: 40 infants undergoing primary eye examination for ROP screening. INTERVENTION: The control group were swaddled, and received 0.2 ml of sterile water given by mouth using a syringe and a soother. The intervention group were swaddled, and received 0.2 ml of sucrose 24% given by mouth using a syringe and a soother. RESULTS: 40 infants were included in the study. There was no difference in mean gestational age at birth, mean birth weight or corrected gestational age at first examination between both groups. The sucrose group had a significantly lower median Neonatal Pain, Agitation and Sedation Scale (N-PASS) score during ROP screening, initially following insertion of the speculum (6.5 vs 5, p=0.02) and subsequently during scleral indentation (9.5 vs 7.5, p=0.03). Fewer infants experienced episodes of desaturations or bradycardia in the intervention group (1 vs 4, p=0.18). CONCLUSION: ROP screening is a necessary but recognised painful procedure. Sucrose combined with NNS and swaddling reduced the behavioural and physiological pain responses. However, pain scores remained consistently high and appropriate pain relief for ROP screening remains a challenge.


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