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dc.contributor.authorKennelly, M M
dc.contributor.authorFarah, N
dc.contributor.authorTurner, M J
dc.contributor.authorStuart, B
dc.date.accessioned2012-02-01T10:58:25Z
dc.date.available2012-02-01T10:58:25Z
dc.date.issued2012-02-01T10:58:25Z
dc.identifier.citationPrenat Diagn. 2010 May;30(5):395-401.en_GB
dc.identifier.issn1097-0223 (Electronic)en_GB
dc.identifier.issn0197-3851 (Linking)en_GB
dc.identifier.pmid20232481en_GB
dc.identifier.doi10.1002/pd.2474en_GB
dc.identifier.urihttp://hdl.handle.net/10147/208038
dc.description.abstractIntrauterine fetal growth restriction (IUGR) is an important pregnancy complication associated with significant adverse clinical outcome, stillbirth, perinatal morbidity and cerebral palsy. To date, no uniformly accepted management protocol of Doppler surveillance that reduces mortality and cognitive morbidity has emerged. Aortic isthmus (AoI) evaluation has been proposed as a potential monitoring tool for IUGR fetuses. In this review, the current knowledge of the relationship between AoI Doppler velocimetry and preterm fetal growth restriction is reviewed. Relevant technical aspects and reproducibility data are reviewed as we discuss AoI Doppler and its place within the existing repertoire of Doppler assessments in placental insufficiency. The AoI is a link between the right and left ventricles which perfuse the lower and upper body, respectively. The clinical use of AoI waveforms for monitoring fetal deterioration in IUGR has been limited, but preliminary work suggests that abnormal AoI impedance indices are an intermediate step between placental insufficiency-hypoxemia and cardiac decompensation. Further prospective studies correlating AoI indices with arterial and venous Doppler indices and perinatal outcome are required before encorporating this index into clinical practice.
dc.language.isoengen_GB
dc.subject.meshAorta/*ultrasonographyen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshFetal Growth Retardation/*ultrasonographyen_GB
dc.subject.meshHumansen_GB
dc.subject.meshLaser-Doppler Flowmetry/*standardsen_GB
dc.subject.meshPlacental Insufficiency/ultrasonographyen_GB
dc.subject.meshPregnancyen_GB
dc.subject.mesh*Ultrasonography, Prenatal/methods/standardsen_GB
dc.titleAortic isthmus Doppler velocimetry: role in assessment of preterm fetal growth restriction.en_GB
dc.contributor.departmentUltrasound and Fetal Medicine Centre, Coombe Women & Infants University Hospital,, Dublin, Ireland. mkennelly@doctors.org.uken_GB
dc.identifier.journalPrenatal diagnosisen_GB
dc.description.provinceLeinster
html.description.abstractIntrauterine fetal growth restriction (IUGR) is an important pregnancy complication associated with significant adverse clinical outcome, stillbirth, perinatal morbidity and cerebral palsy. To date, no uniformly accepted management protocol of Doppler surveillance that reduces mortality and cognitive morbidity has emerged. Aortic isthmus (AoI) evaluation has been proposed as a potential monitoring tool for IUGR fetuses. In this review, the current knowledge of the relationship between AoI Doppler velocimetry and preterm fetal growth restriction is reviewed. Relevant technical aspects and reproducibility data are reviewed as we discuss AoI Doppler and its place within the existing repertoire of Doppler assessments in placental insufficiency. The AoI is a link between the right and left ventricles which perfuse the lower and upper body, respectively. The clinical use of AoI waveforms for monitoring fetal deterioration in IUGR has been limited, but preliminary work suggests that abnormal AoI impedance indices are an intermediate step between placental insufficiency-hypoxemia and cardiac decompensation. Further prospective studies correlating AoI indices with arterial and venous Doppler indices and perinatal outcome are required before encorporating this index into clinical practice.


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