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    A randomised control trial of low glycaemic index carbohydrate diet versus no dietary intervention in the prevention of recurrence of macrosomia.

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    Authors
    Walsh, Jennifer
    Mahony, Rhona
    Foley, Michael
    Mc Auliffe, Fionnuala
    Affiliation
    Department of Obstetrics and Gynaecology, University College Dublin National Maternity Hospital, Dublin, Ireland. jennifer.walsh@ucd.ie
    Issue Date
    2010
    MeSH
    Anthropometry
    Birth Weight
    Body Mass Index
    Diet, Carbohydrate-Restricted
    Female
    Fetal Macrosomia
    Food Habits
    Glycemic Index
    Humans
    Infant, Newborn
    Ireland
    Obesity
    Parity
    Pregnancy
    Pregnancy Complications
    Recurrence
    Risk Factors
    Ultrasonography, Prenatal
    Weight Gain
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    Citation
    A randomised control trial of low glycaemic index carbohydrate diet versus no dietary intervention in the prevention of recurrence of macrosomia. 2010, 10:16 BMC Pregnancy Childbirth
    Journal
    BMC pregnancy and childbirth
    URI
    http://hdl.handle.net/10147/217196
    DOI
    10.1186/1471-2393-10-16
    PubMed ID
    20416041
    Abstract
    Maternal weight and maternal weight gain during pregnancy exert a significant influence on infant birth weight and the incidence of macrosomia. Fetal macrosomia is associated with an increase in both adverse obstetric and neonatal outcome, and also confers a future risk of childhood obesity. Studies have shown that a low glycaemic diet is associated with lower birth weights, however these studies have been small and not randomised 12. Fetal macrosomia recurs in a second pregnancy in one third of women, and maternal weight influences this recurrence risk 3.
    We propose a randomised control trial of low glycaemic index carbohydrate diet vs. no dietary intervention in the prevention of recurrence of fetal macrosomia. Secundigravid women whose first baby was macrosomic, defined as a birth weight greater than 4000 g will be recruited at their first antenatal visit.Patients will be randomised into two arms, a control arm which will receive no dietary intervention and a diet arm which will be commenced on a low glycaemic index diet.The primary outcome measure will be the mean birth weight centiles and ponderal indices in each group.
    Altering the source of maternal dietary carbohydrate may prove to be valuable in the management of pregnancies where there has been a history of fetal macrosomia. Fetal macrosomia recurs in a second pregnancy in one third of women. This randomised control trial will investigate whether or not a low glycaemic index diet can affect this recurrence risk.
    Language
    en
    ISSN
    1471-2393
    Ethical Approval
    N/A
    ae974a485f413a2113503eed53cd6c53
    10.1186/1471-2393-10-16
    Scopus Count
    Collections
    National Maternity Hospital Holles St.

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