• First-line chemotherapy in low-risk gestational trophoblastic neoplasia.

      Alazzam, Mo'iad; Tidy, John; Hancock, Barry W; Osborne, Raymond; Lawrie, Theresa A; Department of Gynaecology, The Galway Clinic, Doughiska, Galway, Ireland. moiad@doctors.org.uk (2012)
      This is an update of a Cochrane review that was first published in Issue 1, 2009. Gestational trophoblastic neoplasia (GTN) is a rare but curable disease arising in the fetal chorion during pregnancy. Most women with low-risk GTN will be cured by evacuation of the uterus with or without single-agent chemotherapy. However, chemotherapy regimens vary between treatment centres worldwide and the comparable benefits and risks of these different regimens are unclear.