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    Mode of conception of triplets and high order multiple pregnancies.

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    Authors
    Basit, I
    Johnson, S N
    Mocanu, E
    Geary, M
    Daly, S
    Wingfield, M
    Affiliation
    Department of Obstetrics and Gynaecology, Coombe Women and Infant's University Hospital, Cork St., Dublin. irambasit@hotmail.com
    Issue Date
    2012-03
    MeSH
    Female
    Fertilization
    Humans
    Ireland
    Pregnancy
    Pregnancy, Multiple
    Reproductive Techniques, Assisted
    Retrospective Studies
    
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    Citation
    Mode of conception of triplets and high order multiple pregnancies. 2012, 105 (3):80-3 Ir Med J
    Journal
    Irish medical journal
    URI
    http://hdl.handle.net/10147/228572
    PubMed ID
    22558814
    Abstract
    A retrospective audit was performed of all high order multiple pregnancies (HOMPs) delivered in three maternity hospitals in Dublin between 1999 and 2008. The mode of conception for each pregnancy was established with a view to determining means of reducing their incidence. A total of 101 HOMPs occurred, 93 triplet, 7 quadruplet and 1 quintuplet. Information regarding the mode of conception was available for 78 (81%) pregnancies. Twenty eight (27.7%) were spontaneous, 34 (33.7%) followedlVF/ICSI/FET treatment (in-vitro fertilisation, intracytoplasmic sperm injection, frozen embryo transfer), 16 (15.8%) resulted from Clomiphene Citrate treatment and 6 (6%) followed ovulation induction with gonadotrophins. Triplet and HOMPs are a major cause of maternal, feta land neonatal morbidity. Many are iatrogenic, arising from fertility treatments including Clomiphene. Reducing the numbers of embryos transferred will address IVF/ICSI/FET-related multiple pregnancy rates and this is currently happening in Ireland. Clomiphene and gonadotrophins should only be prescribed when appropriate resources are available to monitor patients adequately.
    Item Type
    Article
    Language
    en
    ISSN
    0332-3102
    Collections
    Coombe Women & Infants University Hospital

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