Mode of conception of triplets and high order multiple pregnancies.
Affiliation
Department of Obstetrics and Gynaecology, Coombe Women and Infant's University Hospital, Cork St., Dublin. irambasit@hotmail.comIssue Date
2012-03MeSH
FemaleFertilization
Humans
Ireland
Pregnancy
Pregnancy, Multiple
Reproductive Techniques, Assisted
Retrospective Studies
Metadata
Show full item recordCitation
Mode of conception of triplets and high order multiple pregnancies. 2012, 105 (3):80-3 Ir Med JJournal
Irish medical journalPubMed ID
22558814Abstract
A retrospective audit was performed of all high order multiple pregnancies (HOMPs) delivered in three maternity hospitals in Dublin between 1999 and 2008. The mode of conception for each pregnancy was established with a view to determining means of reducing their incidence. A total of 101 HOMPs occurred, 93 triplet, 7 quadruplet and 1 quintuplet. Information regarding the mode of conception was available for 78 (81%) pregnancies. Twenty eight (27.7%) were spontaneous, 34 (33.7%) followedlVF/ICSI/FET treatment (in-vitro fertilisation, intracytoplasmic sperm injection, frozen embryo transfer), 16 (15.8%) resulted from Clomiphene Citrate treatment and 6 (6%) followed ovulation induction with gonadotrophins. Triplet and HOMPs are a major cause of maternal, feta land neonatal morbidity. Many are iatrogenic, arising from fertility treatments including Clomiphene. Reducing the numbers of embryos transferred will address IVF/ICSI/FET-related multiple pregnancy rates and this is currently happening in Ireland. Clomiphene and gonadotrophins should only be prescribed when appropriate resources are available to monitor patients adequately.Item Type
ArticleLanguage
enISSN
0332-3102Collections
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