14-3-3 σ expression effects G2/M response to oxygen and correlates with ovarian cancer metastasis.
Gu, Ting Ting
Carey, Mark S
Hennessy, Bryan T
Bishop, Alexander J R
AffiliationGreehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas, United States of America.
Dose-Response Relationship, Drug
Gene Expression Regulation, Neoplastic
Tumor Cells, Cultured
MetadataShow full item record
Citation14-3-3 σ expression effects G2/M response to oxygen and correlates with ovarian cancer metastasis. 2011, 6 (1):e15864 PLoS ONE
AbstractIn vitro cell culture experiments with primary cells have reported that cell proliferation is retarded in the presence of ambient compared to physiological O₂ levels. Cancer is primarily a disease of aberrant cell proliferation, therefore, studying cancer cells grown under ambient O₂ may be undesirable. To understand better the impact of O₂ on the propagation of cancer cells in vitro, we compared the growth potential of a panel of ovarian cancer cell lines under ambient (21%) or physiological (3%) O₂.
- Dynamic alterations of the extracellular environment of ovarian surface epithelial cells in premalignant transformation, tumorigenicity, and metastasis.
- Authors: Capo-Chichi CD, Smith ER, Yang DH, Roland IH, Vanderveer L, Cohen C, Hamilton TC, Godwin AK, Xu XX
- Issue date: 2002 Oct 15
- Abrogation of taxol-induced G2-M arrest and apoptosis in human ovarian cancer cells grown as multicellular tumor spheroids.
- Authors: Frankel A, Buckman R, Kerbel RS
- Issue date: 1997 Jun 15
- The marine-derived fungal metabolite, terrein, inhibits cell proliferation and induces cell cycle arrest in human ovarian cancer cells.
- Authors: Chen YF, Wang SY, Shen H, Yao XF, Zhang FL, Lai D
- Issue date: 2014 Dec
- [Relationship between raf kinase inhibitor protein and metastasis of ovarian carcinoma].
- Authors: Wang Y, Yang J, Gao Y, Zhao XL, Li HZ, Yao Z
- Issue date: 2009 Jul
- Enhanced c-erbB-2/neu expression in human ovarian cancer cells correlates with more severe malignancy that can be suppressed by E1A.
- Authors: Yu D, Wolf JK, Scanlon M, Price JE, Hung MC
- Issue date: 1993 Feb 15