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dc.contributor.authorNeff, K
dc.contributor.authorDonegan, D
dc.contributor.authorMacMahon, J
dc.contributor.authorO’Hanlon, C
dc.contributor.authorKeane, N
dc.contributor.authorAgha, A
dc.contributor.authorThompson, C
dc.contributor.authorSmith, D
dc.date.accessioned2014-05-16T11:42:45Z
dc.date.available2014-05-16T11:42:45Z
dc.date.issued2014-05
dc.identifier.citationNeff K et al. Management of parenteral nutrition associated hyperglycaemia: A comparison of subcutaneous and intravenous insulin regimen. Ir Med J 2014 May 107(5)en_GB
dc.identifier.urihttp://hdl.handle.net/10147/317073
dc.description.abstractPN is associated with significant hyperglycaemia, which may be detrimental to clinical outcome. There are few data on the management of this phenomenon outside of intensive care units. In our unit, we studied the efficacy of protocol-based intravenous insulin delivery as compared to subcutaneous insulin prescribed individually outside of the critical care setting. In a retrospective review over a two-year period, we compared patients with PN-associated hyperglycaemia who had received both modes of insulin therapy. A total of 122 who developed PN-associated hyperglycaemia were identified. Those on the intravenous insulin regimen were within glycaemic target for more time than those on the subcutaneous regimen (62% Vs 43%, p=0.008). We therefore conclude that outside of the critical care setting, intravenous insulin delivers better glycaemic control and should therefore be considered optimum therapy for patients with PN-associated hyperglycaemia.
dc.languageen
dc.language.isoenen
dc.publisherIrish Medical Jorunalen_GB
dc.subjectNUTRITIONen_GB
dc.subject.otherHYPERGYLCAEMIAen_GB
dc.subject.otherINSULINen_GB
dc.titleManagement of parenteral nutrition associated hyperglycaemia: A comparison of subcutaneous and intravenous insulin regimenen_GB
dc.typeArticleen
dc.identifier.journalIrish Medical Journalen_GB
dc.description.fundingNo fundingen
dc.description.provinceLeinsteren
dc.description.peer-reviewpeer-reviewen
refterms.dateFOA2018-08-30T10:46:00Z
html.description.abstractPN is associated with significant hyperglycaemia, which may be detrimental to clinical outcome. There are few data on the management of this phenomenon outside of intensive care units. In our unit, we studied the efficacy of protocol-based intravenous insulin delivery as compared to subcutaneous insulin prescribed individually outside of the critical care setting. In a retrospective review over a two-year period, we compared patients with PN-associated hyperglycaemia who had received both modes of insulin therapy. A total of 122 who developed PN-associated hyperglycaemia were identified. Those on the intravenous insulin regimen were within glycaemic target for more time than those on the subcutaneous regimen (62% Vs 43%, p=0.008). We therefore conclude that outside of the critical care setting, intravenous insulin delivers better glycaemic control and should therefore be considered optimum therapy for patients with PN-associated hyperglycaemia.


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