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dc.contributor.authorThorne, J
dc.contributor.authorDowney, P
dc.contributor.authorMooney, EE
dc.date.accessioned2014-09-19T11:55:03Z
dc.date.available2014-09-19T11:55:03Z
dc.date.issued2014-09
dc.identifier.citationThorne J, Downey P, Mooney EE. Placental pathology in small for gestational age infants. IMJ 2014 107(8)en_GB
dc.identifier.urihttp://hdl.handle.net/10147/326284
dc.description.abstractInfants with intrauterine growth restriction (IUGR) are at an increased risk of perinatal disease, including death. Many, but not all small for gestational age infants (SGA) have IUGR. Placental disease is an important cause of IUGR, and gross and microscopic examination is critical in explaining such cases. Reports of placentas from infants with a birth weight <2SD from the mean (approx 3rd centile) born between Jan 2004-Dec 2011 were evaluated. The principal pathology was determined in each case. Where two or more pathologic findings were present, they were ranked as principal and co-existing in terms of severity. There were 69,493 deliveries over the study period. 461 SGA cases were identified. No placenta was available in 44 cases, and 21 cases of known anomalies were excluded, leaving a study group of 396 cases. Pathology potentially causing or contributing to SGA and/or IUGR was identified in 84.1% of cases. Significant co-existing pathology was seen in 88 cases (22%). Placental examination provides key information in understanding abnormal fetal growth
dc.language.isoenen
dc.publisherIrish Medical Journalen_GB
dc.subjectCHILDBIRTHen_GB
dc.subjectNEONATEen_GB
dc.titlePlacental pathology in small for gestational age infantsen_GB
dc.typeArticleen
dc.identifier.journalIrish Medical Journalen_GB
dc.description.fundingNo fundingen
dc.description.provinceLeinsteren
dc.description.peer-reviewpeer-reviewen
refterms.dateFOA2018-08-24T18:22:58Z
html.description.abstractInfants with intrauterine growth restriction (IUGR) are at an increased risk of perinatal disease, including death. Many, but not all small for gestational age infants (SGA) have IUGR. Placental disease is an important cause of IUGR, and gross and microscopic examination is critical in explaining such cases. Reports of placentas from infants with a birth weight <2SD from the mean (approx 3rd centile) born between Jan 2004-Dec 2011 were evaluated. The principal pathology was determined in each case. Where two or more pathologic findings were present, they were ranked as principal and co-existing in terms of severity. There were 69,493 deliveries over the study period. 461 SGA cases were identified. No placenta was available in 44 cases, and 21 cases of known anomalies were excluded, leaving a study group of 396 cases. Pathology potentially causing or contributing to SGA and/or IUGR was identified in 84.1% of cases. Significant co-existing pathology was seen in 88 cases (22%). Placental examination provides key information in understanding abnormal fetal growth


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