• The Attractiveness of Opposites: Agonists and Antagonists.

      O'Brien, Tony (2015-02-02)
      ABSTRACT Opioid-induced bowel dysfunction, of which constipation is the most common aspect, is a major limiting factor in the use of opioids for pain management. The availability of an oral, long-acting formulation of oxycodone and naloxone represents a highly significant development in pain management. The combination of an opioid analgesic with an opioid antagonist offers reliable pain control with a significant reduction in the burden of opioid-induced constipation. This report is adapted from paineurope 2014; Issue 3, ©Haymarket Medical Publications Ltd, and is presented with permission. paineurope is provided as a service to pain management by Mundipharma International, LTD and is distributed free of charge to healthcare professionals in Europe. Archival issues can be accessed via the website: http://www.paineurope.com at which European health professionals can register online to receive copies of the quarterly publication.
    • European Pain Federation position paper on appropriate opioid use in chronic pain management.

      O'Brien, T; Christrup, L L; Drewes, A M; Fallon, M T; Kress, H G; McQuay, H J; Mikus, G; Morlion, B J; Perez-Cajaraville, J; Pogatzki-Zahn, E; et al. (2017-01-01)
    • Standards for the management of cancer-related pain across Europe-A position paper from the EFIC Task Force on Cancer Pain.

      Bennett, Michael I; Eisenberg, Elon; Ahmedzai, Sam H; Bhaskar, Arun; O'Brien, Tony; Mercadante, Sebastiano; Krčevski Škvarč, Nevenka; Vissers, Kris; Wirz, Stefan; Wells, Chris; et al. (2019-01-06)