Paediatric cyclical Cushing's disease due to corticotroph cell hyperplasia.
Local subject classificationCUSHING'S DISEASE
Pituitary ACTH Hypersecretion
MetadataShow full item record
CitationPaediatric cyclical Cushing's disease due to corticotroph cell hyperplasia. 2015, 15:27 BMC Endocr Disord
JournalBMC endocrine disorders
AbstractCushing's disease is very rare in the paediatric population. Although uncommon, corticotroph hyperplasia causing Cushing's syndrome has been described in the adult population, but appears to be extremely rare in children. Likewise, cyclical cortisol hypersecretion, while accounting for 15 % of adult cases of Cushing's disease, has only rarely been described in the paediatric population. Here, we describe a very rare case of a 13-year old boy with cyclical cortisol hypersecretion secondary to corticotroph cell hyperplasia.