Gene-trait matching across the Bifidobacterium longum pan-genome reveals considerable diversity in carbohydrate catabolism among human infant strains.
AffiliationUniversity College Cork
Local subject classificationGene-trait-matching
MetadataShow full item record
PublisherIrish Medical Journal
JournalIrish Medical Journal
AbstractBifidobacterium longum is a common member of the human gut microbiota and is frequently present at high numbers in the gut microbiota of humans throughout life, thus indicative of a close symbiotic host-microbe relationship. Different mechanisms may be responsible for the high competitiveness of this taxon in its human host to allow stable establishment in the complex and dynamic intestinal microbiota environment. The objective of this study was to assess the genetic and metabolic diversity in a set of 20 B. longum strains, most of which had previously been isolated from infants, by performing whole genome sequencing and comparative analysis, and to analyse their carbohydrate utilization abilities using a gene-trait matching approach.
The following license files are associated with this item:
- Creative Commons
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 United States
- Fucosyllactose and L-fucose utilization of infant Bifidobacterium longum and Bifidobacterium kashiwanohense.
- Authors: Bunesova V, Lacroix C, Schwab C
- Issue date: 2016 Oct 26
- tuf Gene Sequence Variation in Bifidobacterium longum subsp. infantis Detected in the Fecal Microbiota of Chinese Infants.
- Authors: Lawley B, Centanni M, Watanabe J, Sims I, Carnachan S, Broadbent R, Lee PS, Wong KH, Tannock GW
- Issue date: 2018 Jul 1
- Genomic diversity and distribution of Bifidobacterium longum subsp. longum across the human lifespan.
- Authors: Odamaki T, Bottacini F, Kato K, Mitsuyama E, Yoshida K, Horigome A, Xiao JZ, van Sinderen D
- Issue date: 2018 Jan 8
- Comparative Genomic Analysis of Novel Bifidobacterium longum subsp. longum Strains Reveals Functional Divergence in the Human Gut Microbiota.
- Authors: Díaz R, Torres-Miranda A, Orellana G, Garrido D
- Issue date: 2021 Sep 8
- Targeted High-Resolution Taxonomic Identification of Bifidobacterium longum subsp. infantis Using Human Milk Oligosaccharide Metabolizing Genes.
- Authors: Tso L, Bonham KS, Fishbein A, Rowland S, Klepac-Ceraj V
- Issue date: 2021 Aug 18