Moderate-intensity aerobic and resistance exercise is safe and favorably influences body composition in patients with quiescent Inflammatory Bowel Disease: a randomized controlled cross-over trial.
Authors
Cronin, OwenBarton, Wiley
Moran, Carthage
Sheehan, Donal
Whiston, Ronan
Nugent, Helena
McCarthy, Yvonne
Molloy, Catherine B
O'Sullivan, Orla
Cotter, Paul D
Molloy, Michael G
Shanahan, Fergus
Issue Date
2019-02-12Keywords
Body compositionClinical trials
Exercise
Microbiome
INFLAMMATORY BOWEL DISEASE
PHYSICAL ACTIVITY
Metadata
Show full item recordJournal
BMC gastroenterologyDOI
10.1186/s12876-019-0952-xPubMed ID
30755154Abstract
Improved physical fitness was demonstrated in the exercise group by increases in median estimated VO2max (Baseline: 43.41mls/kg/min; post-intervention: 46.01mls/kg/min; p = 0.03). Improvement in body composition was achieved by the intervention group (n = 13) with a median decrease of 2.1% body fat compared with a non-exercising group (n = 7) (0.1% increase; p = 0.022). Lean tissue mass increased by a median of 1.59 kg and fat mass decreased by a median of 1.52 kg in the exercising group. No patients experienced a deterioration in disease activity scores during the exercise intervention. No clinically significant alterations in the α- and β-diversity of gut microbiota and associated metabolic pathways were evident.Item Type
ArticleLanguage
enEISSN
1471-230Xae974a485f413a2113503eed53cd6c53
10.1186/s12876-019-0952-x
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