Pilot Randomized Controlled Trial of a Standard Versus a Modified Low-Phosphorus Diet in Hemodialysis Patients.

Byrne, Fiona N; Gillman, Barbara A; Kiely, Mairead; Palmer, Brendan; Shiely, Frances; Kearney, Patricia M; Earlie, Joyce; Bowles, Maria B; Keohane, Fiona M; Connolly, Pauline P; Wade, Sarah; Rennick, Theresa A; Moore, Bernice L; Smith, Oonagh N; Sands, Celene M; Slevin, Orla; McCarthy, Denise C; Brennan, Karina M; Mellett, Halóg; Dahly, Darren; Bergin, Eoin; Casserly, Liam F; Conlon, Peter J; Hannan, Kieran; Holian, John; Lappin, David W; O'Meara, Yvonne M; Mellotte, George J; Reddan, Donal; Watson, Alan; Eustace, Joseph

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Affiliation

Department of Nutrition and Dietetics, Cork University Hospital, Cork, Ireland. 2Department of Renal Medicine, Cork University Hospital, Cork, Ireland. 3Health Research Board, Clinical Research Facility, Cork, Ireland. 4Department of Nutrition and Dietetics, Mater Misericordiae University Hospital, Dublin, Ireland. 5Department of Renal Medicine, Mater Misericordiae University Hospital, Dublin, Ireland. 6School of Food and Nutritional Sciences University College Cork, Cork, Ireland. 7School of Public Health, University College Cork, Cork, Ireland. 8Beacon Renal, Tallaght, Dublin, Ireland. 9Department of Nutrition and Dietetics, University Hospital Limerick, Limerick, Ireland. 10Departments of Nephrology and Internal Medicine, University Hospital Limerick, Limerick, Ireland. 11Department of Nutrition and Dietetics, Cavan General Hospital, Cavan, Ireland. 12Department of Medicine, Cavan General Hospital, Cavan, Ireland. 13Department of Nutrition and Dietetics, St. Vincent's University Hospital Dublin, Dublin, Ireland. 14Department of Nephrology, St. Vincent's University Hospital Dublin, Dublin, Ireland. 15Department of Nutrition and Dietetics, Midland Regional Hospital, Tullamore, Ireland. 16Department of Nephrology, Midland Regional Hospital, Tullamore, Ireland. 17Department of Nutrition and Dietetics, Beaumont Hospital, Dublin, Ireland. 18Beaumont Hospital Kidney Center, Beaumont Hospital, Dublin, Ireland. 19Department of Nutrition and Dietetics, Mayo University Hospital, Mayo, Ireland. 20Department of Nutrition and Dietetics, Galway University Hospitals, Galway, Ireland. 21Department of Nephrology, Galway University Hospitals, Galway, Ireland. 22Northern Cross Dialysis Center, Fresenius Medical Care, Dublin, Ireland. 23Beacon Renal Drogheda, Drogheda, Ireland. 24Department of Nutrition and Dietetics, Tallaght University Hospital, Dublin, Ireland. 25Department of Nephrology, Tallaght University Hospital, Dublin, Ireland.

Issue Date

2020-08-18

Keywords

DIET
hyperphosphatemia
phosphates
potassium
renal dialysis

Local subject classification

Access Awards 2021 Submission
Acute Care and Hospitals

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Publisher

Elsevier

Journal

Kidney international reports

URI

http://hdl.handle.net/10147/630706

DOI

10.1016/j.ekir.2020.08.008

PubMed ID

33163715

Additional Links

https://doi.org/10.1016/j.ekir.2020.08.008

Abstract

There was no significant difference in the change in serum phosphate between the standard and modified diets. Although total dietary phosphorus intake was similar, phytate-bound phosphorus, found in pulses, nuts, and whole grains, was significantly higher in the modified diet (P < 0.001). Dietary fiber intake was also significantly higher (P < 0.003), as was the percentage of patients reporting an increase in bowel movements while following the modified diet (P = 0.008). There was no significant difference in the change in serum potassium or in reported protein intake between the 2 diets. Both diets were similarly well tolerated.

Item Type

Article

Language

EISSN

2468-0249

Collections

Cork University Hospital