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dc.contributor.authorCasey, Caoimhe
dc.contributor.authorBuckley, Claire M
dc.contributor.authorKearney, Patricia M
dc.contributor.authorGriffin, Matthew D
dc.contributor.authorDinneen, Sean F
dc.contributor.authorGriffin, Tomás P
dc.date.accessioned2024-12-09T12:39:43Z
dc.date.available2024-12-09T12:39:43Z
dc.date.issued2024-01-27
dc.identifier.pmid38279774
dc.identifier.doi10.1111/jdi.14156
dc.identifier.urihttp://hdl.handle.net/10147/643650
dc.descriptionThere is a large body of literature demonstrating a social gradient in health and increasing evidence of an association between social deprivation and diabetes complications. Diabetic kidney disease (DKD) increases mortality in people with diabetes. Socioeconomic deprivation is increasingly recognized as a modifier of risk factors for kidney disease but also an independent risk factor itself for kidney disease. This may not be truly appreciated by clinicians and warrants further attention and exploration. In this review we explore the literature to date from Europe on the relationship between social deprivation and DKD. The majority of the studies showed at least an association with microalbuminuria, an early marker of DKD, while many showed an association with overt nephropathy. This was seen across many countries in Europe using a variety of different measures of deprivation. We reviewed and considered the mechanisms by which deprivation may lead to DKD. Health related behaviors such as smoking and suboptimal control of risk factors such as hypertension, hyperglycemia and elevated body mass index (BMI) accounts for some but not all of the association. Poorer access to healthcare, health literacy, and stress are also discussed as potential mediators of the association. Addressing deprivation is difficult but starting points include targeted interventions for people living in deprived circumstances, equitable roll out of diabetes technology, and flexible outpatient clinic arrangements including virtual and community‐based care.en_US
dc.language.isoenen_US
dc.rights© 2024 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd.
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectDIABETES MELLITUSen_US
dc.subjectDiabetic kidney diseaseen_US
dc.subjectsocial deprivationen_US
dc.titleSocial deprivation and diabetic kidney disease: A European view.en_US
dc.typeArticleen_US
dc.typeOtheren_US
dc.identifier.eissn2040-1124
dc.identifier.journalJournal of diabetes investigationen_US
dc.source.journaltitleJournal of diabetes investigation
dc.source.volume15
dc.source.issue5
dc.source.beginpage541
dc.source.endpage556
refterms.dateFOA2024-12-09T12:39:45Z
dc.source.countryJapan


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© 2024 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd.
Except where otherwise noted, this item's license is described as © 2024 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd.