Estrogenic Plants: to Prevent Neurodegeneration and Memory Loss and Other Symptoms in Women After Menopause.

Echeverria, Valentina; Echeverria, Florencia; Barreto, George E; Echeverría, Javier; Mendoza, Cristhian

dc.contributor.author	Echeverria, Valentina
dc.contributor.author	Echeverria, Florencia
dc.contributor.author	Barreto, George E
dc.contributor.author	Echeverría, Javier
dc.contributor.author	Mendoza, Cristhian
dc.date.accessioned	2025-02-27T10:50:02Z
dc.date.available	2025-02-27T10:50:02Z
dc.date.issued	2021-05-20
dc.identifier.issn	1663-9812
dc.identifier.pmid	34093183
dc.identifier.doi	10.3389/fphar.2021.644103
dc.identifier.uri	http://hdl.handle.net/10147/644454
dc.description	In mammals, sexual hormones such as estrogens play an essential role in maintaining brain homeostasis and function. Estrogen deficit in the brain induces many undesirable symptoms such as learning and memory impairment, sleep and mood disorders, hot flushes, and fatigue. These symptoms are frequent in women who reached menopausal age or have had ovariectomy and in men and women subjected to anti-estrogen therapy. Hormone replacement therapy alleviates menopause symptoms; however, it can increase cardiovascular and cancer diseases. In the search for therapeutic alternatives, medicinal plants and specific synthetic and natural molecules with estrogenic effects have attracted widespread attention between the public and the scientific community. Various plants have been used for centuries to alleviate menstrual and menopause symptoms, such as Cranberry, Ginger, Hops, Milk Thistle, Red clover, Salvia officinalis, Soy, Black cohosh, Turnera diffusa, Ushuva, and Vitex. This review aims to highlight current evidence about estrogenic medicinal plants and their pharmacological effects on cognitive deficits induced by estrogen deficiency during menopause and aging.	en_US
dc.language.iso	en	en_US
dc.rights	Copyright © 2021 Echeverria, Echeverria, Barreto, Echeverría and Mendoza.
dc.rights	Attribution 4.0 International	*
dc.rights.uri	http://creativecommons.org/licenses/by/4.0/	*
dc.subject	Alzheimer's disease	en_US
dc.subject	Parkinson's disease	en_US
dc.subject	cognitive impairment	en_US
dc.subject	estrogenic plants	en_US
dc.subject	MENOPAUSE	en_US
dc.subject	neurodegeneration	en_US
dc.subject	neuroprotection	en_US
dc.title	Estrogenic Plants: to Prevent Neurodegeneration and Memory Loss and Other Symptoms in Women After Menopause.	en_US
dc.type	Article	en_US
dc.identifier.journal	Frontiers in pharmacology	en_US
dc.source.journaltitle	Frontiers in pharmacology
dc.source.volume	12
dc.source.beginpage	644103
dc.source.endpage
refterms.dateFOA	2025-02-27T10:50:03Z
dc.source.country	Switzerland