• Angiogenin levels and ANG genotypes: dysregulation in amyotrophic lateral sclerosis.

      McLaughlin, Russell Lewis; Phukan, Julie; McCormack, William; Lynch, David S; Greenway, Matthew; Cronin, Simon; Saunders, Jean; Slowik, Agnieska; Tomik, Barbara; Andersen, Peter M; et al. (PLoS One, 2010-11)
      To determine whether 5 single nucleotide polymorphisms (SNPs) associate with ALS in 3 different populations. We also assessed the contribution of genotype to angiogenin levels in plasma and CSF.
    • Sequencing and analysis of an Irish human genome.

      Tong, Pin; Prendergast, James G D; Lohan, Amanda J; Farrington, Susan M; Cronin, Simon; Friel, Nial; Bradley, Dan G; Hardiman, Orla; Evans, Alex; Wilson, James F; et al. (2010)
      Recent studies generating complete human sequences from Asian, African and European subgroups have revealed population-specific variation and disease susceptibility loci. Here, choosing a DNA sample from a population of interest due to its relative geographical isolation and genetic impact on further populations, we extend the above studies through the generation of 11-fold coverage of the first Irish human genome sequence.